Structure of PDB 4csf Chain E Binding Site BS01

Receptor Information
>4csf Chain E (length=249) Species: 11590 (Toscana virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENYRDIALAFLDESADSGTINAWVNEFAYEGFDPKRIVQLVKERGTAKGR
DWKKDVKMMIVLNLVRGNKPEAMMKKMSEKGASIVANLISVYQLKEGNPG
RDTITLSRVSAAFVPWTVQALRVLSESLPVSGTTMDAIAGVTYPRAMMHP
SFAGIIDLDLPNGAGATIADAHGLFMIEFSKTINPSLRTKQANEVAATFE
KPNMAAMSGRFFTREDKKKLLIAVGIIDEDLVLASAVVRSAEKYRAKVG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4csf Structural Insights Into RNA Encapsidation and Helical Assembly of the Toscana Virus Nucleoprotein.
Resolution2.598 Å
Binding residue
(original residue number in PDB)		Y32 F35 N71 G100 N101 P102 S110 R111 T185 I186 P188 R191 T201 K204 P205 M207 A208 A209 S211
Binding residue
(residue number reindexed from 1)		Y29 F32 N68 G97 N98 P99 S107 R108 T182 I183 P185 R188 T198 K201 P202 M204 A205 A206 S208
Binding affinityPDBbind-CN: Kd=260nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044172 host cell endoplasmic reticulum-Golgi intermediate compartment
GO:0044177 host cell Golgi apparatus
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4csf, PDBe:4csf, PDBj:4csf
PDBsum4csf
PubMed24688060
UniProtP21701|NCAP_TOSV Nucleoprotein (Gene Name=N)

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