Structure of PDB 3u6n Chain E Binding Site BS01

Receptor Information
>3u6n Chain E (length=585) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFK
RHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIM
RVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAG
FIAQSCLAQGLSTMLANLFSMRSYIKIEEDTWQKYYLEGVANEMYTEYLS
SAFVGLSFPTVCELCYVKLKLLLIAIEYKKRILINPGNHVKMQEGTLGFF
IASDAKEVKRAFFKRYDSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVV
VCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRREWETL
HNFPKVFILPGTPLSRADLRAVNINLCDMCVILSANASLQDKECILASLN
IKSMQFDTTGSNIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGT
AFAVSVLDSLMSATYFNDNILTLIRTLVTGGALEALLAEENALRGGYSTP
QTLANRDRCRVAQLALYDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYR
LRDAPSQCTKRYVITNPPYEFEMVPTDLIFCLMQF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3u6n Chain E Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3u6n Open structure of the Ca(2+) gating ring in the high-conductance Ca(2+)-activated K(+) channel.
Resolution3.61 Å
Binding residue
(original residue number in PDB)		Q893 D896 Q897 D899 D901
Binding residue
(residue number reindexed from 1)		Q426 D429 Q430 D432 D434
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:3u6n, PDBe:3u6n, PDBj:3u6n
PDBsum3u6n
PubMed22139424
UniProtB7ZC96|KCMA1_DANRE Calcium-activated potassium channel subunit alpha-1a (Gene Name=kcnma1a)

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