Structure of PDB 3prk Chain E Binding Site BS01

Receptor Information
>3prk Chain E (length=279) Species: 37998 (Parengyodontium album) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFE
GRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVAKKTQLFGVKVLDDNG
SGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQS
SGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLD
IFGPGTSILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACR
YIADTANKGDLSNIPFGTVNLLAYNNYQA
Ligand information
Receptor-Ligand Complex Structure
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PDB3prk Inhibition of proteinase K by methoxysuccinyl-Ala-Ala-Pro-Ala-chloromethyl ketone. An x-ray study at 2.2-A resolution.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		H69 L96 G100 G102 Y104 S132 L133 G134 N161 S224
Binding residue
(residue number reindexed from 1)		H69 L96 G100 G102 Y104 S132 L133 G134 N161 S224
Enzymatic activity
Catalytic site (original residue number in PDB) S224
Catalytic site (residue number reindexed from 1) S224
Enzyme Commision number 3.4.21.64: peptidase K.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3prk, PDBe:3prk, PDBj:3prk
PDBsum3prk
PubMed1894649
UniProtP06873|PRTK_PARAQ Proteinase K (Gene Name=PROK)

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