Structure of PDB 3pgc Chain E Binding Site BS01

Receptor Information
>3pgc Chain E (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTV
YPSNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLV
MLETVPRSGEVYTCQVEHPSVTSPLTVEWR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pgc Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Resolution2.66 Å
Binding residue
(original residue number in PDB)		W9 F13 Y47 D57 Y60 W61 L67 R71 Y78 H81 N82 V85
Binding residue
(residue number reindexed from 1)		W8 F12 Y46 D56 Y59 W60 L66 R70 Y77 H80 N81 V84
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3pgc, PDBe:3pgc, PDBj:3pgc
PDBsum3pgc
PubMed21115828
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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