Structure of PDB 3ovg Chain E Binding Site BS01

Receptor Information
>3ovg Chain E (length=351) Species: 262723 (Mycoplasmopsis synoviae 53) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NKFARTVLGDIPVEKLGITDCHDHFIKNGGPEVEEHIDFLMLNVDASIKE
FKEFIDRGGSTIVTMDPPNVGRDVLKTLEIANAVKNLGGNVIMSTGFHKA
KFYDKYSSWLAVVPTEEIVKMCVAEIEEGMDEYNYNGPVVKRSKAKAGII
KAGTGYGAIDRLELKALEVAARTSILTGCPILVHTQLGTMALEVAKHLIG
FGANPDKIQISHLNKNPDKYYYEKVIKETGVTLCFDGPDRVKYYPDSLLA
ENIKYLVDKGLQKHITLSLDAGRILYQRNYGLTKGKQTFGLAYLFDRFLP
LLKQVGVSKEAIFDILVNNPKRVLAFDEKRNFDPLKVSKEVLELKKELNL
N
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3ovg Chain E Residue 362 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ovg The crystal structure of an amidohydrolase from Mycoplasma synoviae with Zn ion bound
Resolution2.059 Å
Binding residue
(original residue number in PDB)		K153 H186 H214
Binding residue
(residue number reindexed from 1)		K151 H184 H212
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H24 H26 K153 H186 H214 K217 G239 D272
Catalytic site (residue number reindexed from 1) H22 H24 K151 H184 H212 K215 G237 D270
Enzyme Commision number 3.1.1.104: 5-phospho-D-xylono-1,4-lactonase.
3.1.1.25: 1,4-lactonase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050490 1,4-lactonase activity
Biological Process
GO:0009056 catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3ovg, PDBe:3ovg, PDBj:3ovg
PDBsum3ovg
PubMed
UniProtQ4A724|PFLAC_MYCS5 Phospho-furanose lactonase (Gene Name=MS53_0025)

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