Structure of PDB 3mq6 Chain E Binding Site BS01

Receptor Information
>3mq6 Chain E (length=333) Species: 1911 (Streptomyces griseus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PFTYSIEATRNLATTERCIQDIRNRSTQFQLAQQNMLAYTFGEVIPGFAS
AGINGMDYRDVIGRPVENAVTEGTHFFRDDFRVDSNAKAKVAGDIFEIVS
SAVMWNCAARWNSLMVGEGWRSQPRYSRPTLSPSPRRQVAVLNLPRSFDW
VSLLVPESQEVIEEFRAGLRKDGLGLPTSTPDLAVVVLPEEFQNDEMWRE
EIAGLTRPNQILLSGAYQRLQGRVQPGEISLAVAFKRSLRSDRLYQPLYE
ANVMQLLLEGKLGAPKVEFEVHTLAPEGTNAFVTYEAASLYGLAEGRSAV
HRAIRELYVPPTAADLARRFFAFLNERMELVNG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mq6 Domain swapping in allosteric modulation of DNA specificity.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
R31 T33 Q36 L37 Q39 Q40 N92 A93 K96 R152 R246 S247 D248
Binding residue
(residue number reindexed from 1)
R25 T27 Q30 L31 Q33 Q34 N86 A87 K90 R146 R240 S241 D242
Binding affinityPDBbind-CN: Kd=0.6nM
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0042802 identical protein binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3mq6, PDBe:3mq6, PDBj:3mq6
PDBsum3mq6
PubMed21151881
UniProtQ9F6L0

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