Structure of PDB 3l6y Chain E Binding Site BS01

Receptor Information
>3l6y Chain E (length=397) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK
GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR
LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGW
EREPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQA
EIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYSPARGYELLFQPEV
VRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSA
IADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPNFSE
DTVISILNTINEVIAEGIEKLVLINKSRSEKEVRAAALVLQTIWGYK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3l6y Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		N362 M374 F377 N385 A386 A388 Y389 Q391 H392 Y395 R396 K401 K433 N434 F437 G438 K444 W477 N478 S481 K486 N536 K574
Binding residue
(residue number reindexed from 1)		N4 M16 F19 N27 A28 A30 Y31 Q33 H34 Y37 R38 K43 K75 N76 F79 G80 K86 W119 N120 S123 K128 N172 K210
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0098609 cell-cell adhesion

View graph for
Biological Process
External links
PDB RCSB:3l6y, PDBe:3l6y, PDBj:3l6y
PDBsum3l6y
PubMed20371349
UniProtO60716|CTND1_HUMAN Catenin delta-1 (Gene Name=CTNND1)

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