Structure of PDB 3er5 Chain E Binding Site BS01

Receptor Information
>3er5 Chain E (length=330) Species: 5116 (Cryphonectria parasitica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTA
SEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLT
VTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKA
SLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTST
GYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGG
YVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGI
GINIFGDVALKAAFVVFNGATTPTLGFASK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3er5 X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D12 D32 G34 S74 Y75 G76 D77 I117 D215 G217 T218 T219
Binding residue
(residue number reindexed from 1)		D15 D35 G37 S78 Y79 G80 D81 I122 D219 G221 T222 T223
Enzymatic activity
Enzyme Commision number 3.4.23.22: endothiapepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3er5, PDBe:3er5, PDBj:3er5
PDBsum3er5
PubMed8424781
UniProtP11838|CARP_CRYPA Endothiapepsin (Gene Name=EAPA)

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