Structure of PDB 3e1k Chain E Binding Site BS01

Receptor Information
>3e1k Chain E (length=393) Species: 28985 (Kluyveromyces lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSRPIRVGFVGLTSGKSWVAKTHFLAIQQLSSQFQIVALYNPTLKSSLQT
IEQLQLKHATGFDSLESFAQYKDIDMIVVSVKVPEHYEVVKNILEHSSQN
LNLRYLYVEWALAASVQQAEELYSISQQRANLQTIICLQGRKSPYIVRAK
ELISEGCIGDINSIEISGNGGWYGYERPMRSPEYLYDIESGVNLISNSFG
HTIDVLQYITGSYFQKINAMISNNIPTQFLLDENGKRTKETISKTCPDHL
LFQGILENGKVPVSCSFKGGTPVKKLTKNLVIDIHGTKGDLKIEGDAGFV
EISNLVLYFYGIKNGEEQTMEVFHLRNYNSVVGNILRIYESIADYHFLKF
DKQGFRFEGFPTFKDAIILHRLIDAVFRSDKEEKTLDVSKIMI
Ligand information
>3e1k Chain F (length=14) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LFNTTTMDDVYNYI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3e1k The Interaction between an Acidic Transcriptional Activator and Its Inhibitor: THE MOLECULAR BASIS OF Gal4p RECOGNITION BY Gal80p.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		K34 G184 W185 P191 D309 A310 F312 S316 N317 H370 R372 V377
Binding residue
(residue number reindexed from 1)		K21 G171 W172 P178 D296 A297 F299 S303 N304 H324 R326 V331
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
Biological Process
GO:0006012 galactose metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3e1k, PDBe:3e1k, PDBj:3e1k
PDBsum3e1k
PubMed18701455
UniProtQ06433|GAL80_KLULA Galactose/lactose metabolism regulatory protein GAL80 (Gene Name=GAL80)

[Back to BioLiP]