Structure of PDB 2ykr Chain E Binding Site BS01

Receptor Information
>2ykr Chain E (length=150) Species: 668369 (Escherichia coli DH5[alpha]) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAA
IQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGG
AMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGK
Ligand information
>2ykr Chain A (length=1533) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacga
guggcggacgggugaguaaugucugggaaacugccugauggagggggaua
acuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagagg
gggaccuucgggccucuugccaucggaugugcccagaugggauuagcuag
uaggugggguaacggcucaccuaggcgacgaucccuagcuggucugagag
gaugaccagccacacuggaacugagacacgguccagacuccuacgggagg
cagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugcc
gcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagga
agggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaagc
accggcuaacuccgugccagcagccgcgguaauacggagggugcaagcgu
uaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaagucag
augugaaauccccgggcucaaccugggaacugcaucugauacuggcaagc
uugagucucguagagggggguagaauuccagguguagcggugaaaugcgu
agagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagacu
gacgcucaggugcgaaagcguggggagcaaacaggauuagauacccuggu
aguccacgccguaaacgaugucgacuuggagguugugcccuugaggcgug
gcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgcaa
gguuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcaug
ugguuuaauucgaugcaacgcgaagaaccuuaccuggucuugacauccac
ggaaguuuucagagaugagaaugugccuucgggaaccgugagacaggugc
ugcauggcugucgucagcucguguugugaaauguuggguuaagucccgca
acgagcgcaacccuuauccuuuguugccagcgguccggccgggaacucaa
aggagacugccagugauaaacuggaggaagguggggaugacgucaaguca
ucauggcccuuacgaccagggcuacacacgugcuacaauggcgcauacaa
agagaagcgaccucgcgagagcaagcggaccucauaaagugcgucguagu
ccggauuggagucugcaacucgacuccaugaagucggaaucgcuaguaau
cguggaucagaaugccacggugaauacguucccgggccuuguacacaccg
cccgucacaccaugggaguggguugcaaaagaaguagguagcuuaaccuu
cgggagggcgcuuaccacuuugugauucaugacuggggugaagucguaac
aagguaaccguaggggaaccugcgguuggauca
.......<<<<..[.(((..>>>>......<<<<<..<<<<<........
<<..<<...........<....<.....................>..>..
...........<..........<<<<........<<<<<...<.<.....
.<<............>>.......>.>....................<<.
.....<....>....>>....>>>>>......>>>>..<<<.........
.<<<<.............>>>>..........>>>..<<<<..<<....>
>.....>>>>..>..<<<<............>>>>...............
...>>.>>.........<<.....<<<<....>>>>...>>......>>>
>>.............<<<....>>>...............<<<<<.....
.<.........................>........>>>>>.......<<
<<<(((...<<<<.........)))..........>>>>>>>>>..>>>>
>.................((......<<<...<......<..<.<<...<
<<<........<<<<.......>>>>......>>>>.....>>>..>...
...<<<<<<.....<<<<<......<.<.<.<..................
.....>.>.>..>..........<<....>>...>>>>>....>>.>>>>
.....>...>>>.....<<<<<.....<....<.............>...
.>..>>>>>..........<<<<<<..<<<<<<<<<<.........>>>>
>>>>>>...<<..))>>.....>>>>>>.....<<........<......
..>......>>...))).]..<...<<<<<<<.....<<<....<<<<<<
<...............................<<<<<<........<<<<
<.......<<<....>>>.......<<....>>...>>>>.>..<<<.<<
<..<.<<<........<<<<<<<<......>>....<........>....
>>>>>>............<<<..........<<.....>>.........>
>>.........<<<.....>>>........................>...
>>.>>>>>>>....>>>>>>.......>>>>>>>......<<.<......
.<<<..<<...<<<....>>>...>>....>>>.......>.>>......
......<<<<<.<........>.>>>>>............>>>.....<<
<..<...........>..>>>...........>>>>>>>..>........
.......<<<<.<.......<<<<<........<<.......<<..<<..
..>>.>>......>>.......>>>>>.......>.>>>>..........
.....<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB2ykr Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Resolution9.8 Å
Binding residue
(original residue number in PDB)
R19 V20 S21 K22 T23 K25 G27 R28 F30 T33 Y49 K51 A52 R53 K61 H88 T89 G90 R92 Q96 A98 T102 G103 I104 I105 A106 G107 M110 L123 A124 K125 A126 Y127 G128 T130 N131 I133 N134 R137
Binding residue
(residue number reindexed from 1)
R11 V12 S13 K14 T15 K17 G19 R20 F22 T25 Y41 K43 A44 R45 K53 H80 T81 G82 R84 Q88 A90 T94 G95 I96 I97 A98 G99 M102 L115 A116 K117 A118 Y119 G120 T122 N123 I125 N126 R129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2ykr, PDBe:2ykr, PDBj:2ykr
PDBsum2ykr
PubMed21788480
UniProtP0A7W1|RS5_ECOLI Small ribosomal subunit protein uS5 (Gene Name=rpsE)

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