Structure of PDB 2w2q Chain E Binding Site BS01

Receptor Information
>2w2q Chain E (length=47) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LYFQGAMGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2w2q Chain E Residue 1333 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2w2q Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
Resolution2.33 Å
Binding residue
(original residue number in PDB)		T294 E296 D310 L311 G314
Binding residue
(residue number reindexed from 1)		T9 E11 D25 L26 G29
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2w2q, PDBe:2w2q, PDBj:2w2q
PDBsum2w2q
PubMed19001363
UniProtP01130|LDLR_HUMAN Low-density lipoprotein receptor (Gene Name=LDLR)

[Back to BioLiP]