Structure of PDB 2hnt Chain E Binding Site BS01
Receptor Information
>2hnt Chain E (length=67) Species:
9606
(Homo sapiens) [
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EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRET
AASLLQAGYKGRVTGWG
Ligand information
>2hnt Chain L (length=28) Species:
9606
(Homo sapiens) [
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ADCGLRPLFEKKSLEDKTERELLESYID
Receptor-Ligand Complex Structure
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PDB
2hnt
Crystallographic structure of human gamma-thrombin.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
D116 H119 C122 L129C Y134 K135 R137
Binding residue
(residue number reindexed from 1)
D38 H41 C44 L54 Y59 K60 R62
Enzymatic activity
Enzyme Commision number
3.4.21.5
: thrombin.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:2hnt
,
PDBe:2hnt
,
PDBj:2hnt
PDBsum
2hnt
PubMed
8071320
UniProt
P00734
|THRB_HUMAN Prothrombin (Gene Name=F2)
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