Structure of PDB 2f54 Chain E Binding Site BS01
Receptor Information
>2f54 Chain E (length=241) Species:
9606
(Homo sapiens) [
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GVTQTPKFQVLKTGQSMTLQCAQDMNHEYMSWYRQDPGMGLRLIHYSVGA
GITDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASSYVGNTGEL
FFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPD
HVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQD
PRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
Ligand information
>2f54 Chain C (length=9) Species:
9606
(Homo sapiens) [
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SLLMWITQC
Receptor-Ligand Complex Structure
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PDB
2f54
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
E28 Y93 V94 G95 N96
Binding residue
(residue number reindexed from 1)
E28 Y93 V94 G95 N96
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2f54
,
PDBe:2f54
,
PDBj:2f54
PDBsum
2f54
PubMed
16600963
UniProt
P01850
|TRBC1_HUMAN T cell receptor beta constant 1 (Gene Name=TRBC1)
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