Structure of PDB 1ylo Chain E Binding Site BS01

Receptor Information
>1ylo Chain E (length=346) Species: 198215 (Shigella flexneri 2a str. 2457T) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMDLSLLKALSEADAIASSEQEVRQILLEEAARLQKEVRFDGLGSVLIRL
NESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRI
TTREECKIPGLLDGDRQGNDVSAMRVDIGARTYDEVMQAGIRPGDRVTFD
TTFQVLPHQRVMGKAFDDRLSCYLLVTLLRELHDAELPAEVWLVASSSEE
VGLRGGQTATRAVSPDVAIVLDTACWAKNFDYGAANHRQIGNGPMLVLSD
KSLIAPPKLTAWIETVAAEIGVPLQADMFSNGGTDGGAVHLTGTGVPTLV
MGPATRHGHCAASIADCRDILQMEQLLSALIQRLTRETVVQLTDFR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1ylo Chain E Residue 1846 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ylo Crystal Structure of hypothetical protein from Shigella flexneri 2a.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		H62 D166 D221
Binding residue
(residue number reindexed from 1)		H63 D167 D222
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1ylo, PDBe:1ylo, PDBj:1ylo
PDBsum1ylo
PubMed
UniProtA0A0H2VWV0

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