Structure of PDB 1xdk Chain E Binding Site BS01

Receptor Information

>1xdk Chain E (length=217) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ANEDMPVEKILEAELAVEPPNDPVTNICQAADKQLFTLVEWAKRIPHFSE
LPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAG
VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEA
LREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL
IGDTPIDTFLMEMLEAP

Ligand information

>1xdk Chain G (length=11) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

NHPMLMNLLKD

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1xdk CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES
Resolution	2.9 Å
Binding residue (original residue number in PDB)	V285 K289 L299 V303 R307 F455 E458 P463
Binding residue (residue number reindexed from 1)	V39 K43 L53 V57 R61 F209 E212 P217

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003707	nuclear steroid receptor activity
GO:0008270	zinc ion binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus

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Cellular Component

External links

PDB	RCSB:1xdk, PDBe:1xdk, PDBj:1xdk
PDBsum	1xdk
PubMed	15528208
UniProt	P28700\|RXRA_MOUSE Retinoic acid receptor RXR-alpha (Gene Name=Rxra)

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