Structure of PDB 1tze Chain E Binding Site BS01
Receptor Information
>1tze Chain E (length=98) Species:
9606
(Homo sapiens) [
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MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
Ligand information
>1tze Chain I (length=7) [
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KPFYVNV
Receptor-Ligand Complex Structure
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PDB
1tze
Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
R67 R86 S88 S90 S96 H107 F108 K109 W121
Binding residue
(residue number reindexed from 1)
R13 R32 S34 S36 S42 H53 F54 K55 W67
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1tze
,
PDBe:1tze
,
PDBj:1tze
PDBsum
1tze
PubMed
8673601
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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