Structure of PDB 1tjl Chain E Binding Site BS01

Receptor Information
>1tjl Chain E (length=145) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRILEAWRNQLRDEVD
RTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKV
EDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1tjl Chain E Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1tjl Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription
Resolution2.0 Å
Binding residue
(original residue number in PDB)		C114 C135 C138
Binding residue
(residue number reindexed from 1)		C108 C129 C132
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006302 double-strand break repair
GO:0010468 regulation of gene expression
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1tjl, PDBe:1tjl, PDBj:1tjl
PDBsum1tjl
PubMed15294156
UniProtP0ABS1|DKSA_ECOLI RNA polymerase-binding transcription factor DksA (Gene Name=dksA)

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