Structure of PDB 1szz Chain E Binding Site BS01

Receptor Information

>1szz Chain E (length=171) Species: 173 (Leptospira interrogans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SVRKILRMGDPILRKISEPVTEDEIQTKEFKKLIRDMFTTMRHAEGVGLA
APQIGILKQIVVVGSEDNERYPGTPDVPERIILNPVITPLTKDTSGFWEG
CLSVPGMRGYVERPNQIRMQWMDEKGNQFDETIDGYKAIVYQHECDHLQG
ILYVDRLKDTKLFGFNETLDS

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

1szz Chain E Residue 720 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1szz Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
Resolution	3.3 Å
Binding residue (original residue number in PDB)	C101 H143 H147
Binding residue (residue number reindexed from 1)	C101 H143 H147
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	G48 Q53 C101 L102 H143 E144 H147
Catalytic site (residue number reindexed from 1)	G48 Q53 C101 L102 H143 E144 H147
Enzyme Commision number	3.5.1.88: peptide deformylase.

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0042586	peptide deformylase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006412	translation
GO:0043686	co-translational protein modification

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Molecular Function

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Biological Process

External links

PDB	RCSB:1szz, PDBe:1szz, PDBj:1szz
PDBsum	1szz
PubMed	16239225
UniProt	Q93LE9\|DEF_LEPIN Peptide deformylase (Gene Name=def)

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