Structure of PDB 1rta Chain E Binding Site BS01

Receptor Information
>1rta Chain E (length=124) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHES
LADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTT
QANKHIIVACEGNPYVPVHFDASV
Ligand information
Receptor-Ligand Complex Structure
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PDB1rta Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H12 R39 C40 K41 P42 T45 N71 A109 E111 V118 H119 F120
Binding residue
(residue number reindexed from 1)		H12 R39 C40 K41 P42 T45 N71 A109 E111 V118 H119 F120
Enzymatic activity
Catalytic site (original residue number in PDB) H12 K41 H119 F120 D121
Catalytic site (residue number reindexed from 1) H12 K41 H119 F120 D121
Enzyme Commision number 4.6.1.18: pancreatic ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004522 ribonuclease A activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0016829 lyase activity
Biological Process
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1rta, PDBe:1rta, PDBj:1rta
PDBsum1rta
PubMed1429575
UniProtP61823|RNAS1_BOVIN Ribonuclease pancreatic (Gene Name=RNASE1)

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