Structure of PDB 1rf1 Chain E Binding Site BS01

Receptor Information
>1rf1 Chain E (length=295) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEI
IRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGR
KWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEM
EDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGEN
RTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNG
RYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
Ligand information
Receptor-Ligand Complex Structure
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PDB1rf1 Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Resolution2.53 Å
Binding residue
(original residue number in PDB)		N364 M367 W385 E397 D398 R406 C407 H408 T431 D432 M438
Binding residue
(residue number reindexed from 1)		N200 M203 W221 E233 D234 R242 C243 H244 T267 D268 M274
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1rf1, PDBe:1rf1, PDBj:1rf1
PDBsum1rf1
PubMed14992585
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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