Structure of PDB 1p84 Chain E Binding Site BS01

Receptor Information

>1p84 Chain E (length=185) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KSTYRTPNFDDVLKENNDADKGRSYAYFMVGAMGLLSSAGAKSTVETFIS
SMTATADVLAMAKVEVNLAAIPLGKNVVVKWQGKPVFIRHRTPHEIQEAN
SVDMSALKDPQTDADRVKDPQWLIMLGICTHLGCVPIGEAGDFGGWFCPC
HGSHYDISGRIRKGPAPLNLEIPAYEFDGDKVIVG

Ligand information

InChI=1S/2Fe.2S

NIXDOXVAJZFRNF-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04	[Fe]1S[Fe]S1
CACTVS 3.341 OpenEye OEToolkits 1.5.0	S1[Fe]S[Fe]1

Formula

Fe2 S2

Name

FE2/S2 (INORGANIC) CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

1p84 Chain E Residue 704 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	1p84 Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound
Resolution	2.5 Å
Binding residue (original residue number in PDB)	C159 H161 L162 C178 C180 H181 S183
Binding residue (residue number reindexed from 1)	C129 H131 L132 C148 C150 H151 S153
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H181
Catalytic site (residue number reindexed from 1)	H151
Enzyme Commision number	7.1.1.8: quinol--cytochrome-c reductase.

Gene Ontology

	Molecular Function
GO:0008121	ubiquinol-cytochrome-c reductase activity
GO:0051537	2 iron, 2 sulfur cluster binding

	Cellular Component
GO:0016020	membrane

View graph for
Molecular Function

View graph for
Cellular Component

External links

PDB	RCSB:1p84, PDBe:1p84, PDBj:1p84
PDBsum	1p84
PubMed	12782631
UniProt	P08067\|UCRI_YEAST Cytochrome b-c1 complex subunit Rieske, mitochondrial (Gene Name=RIP1)

[Back to BioLiP]