Structure of PDB 1m32 Chain E Binding Site BS01

Receptor Information
>1m32 Chain E (length=361) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNIGVVEQIRQQLTALATASE
GYTSVLLQGSGSYAVEAVLGSALGPQDKVLIVSNGAYGARMVEMAGLMGI
AHHAYDCGEVARPDVQAIDAILNADPTISHIAMVHSETTTGMLNPIDEVG
ALAHRYGKTYIVDAMSSFGGIPMDIAALHIDYLISSANKCIQGVPGFAFV
IAREQKLAACKGHSRSLSLDLYAQWRCMEDNHGKWRFTSPTHTVLAFAQA
LKELAKEGGVAARHQRYQQNQRSLVAGMRALGFNTLLDDELHSPIITAFY
SPEDPQYRFSEFYRRLKEQGFVIYPGKVSQSDCFRIGNIGEVYAADITAL
LTAIRTAMYWT
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain1m32 Chain E Residue 4605 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1m32 Degradation Pathway of the Phosphonate Ciliatine: Crystal Structure of 2-Aminoethylphosphonate Transaminase
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Y91 Y328
Binding residue
(residue number reindexed from 1)		Y87 Y324
Annotation score1
Enzymatic activity
Enzyme Commision number 2.6.1.37: 2-aminoethylphosphonate--pyruvate transaminase.
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0047304 2-aminoethylphosphonate-pyruvate transaminase activity
Biological Process
GO:0019700 organic phosphonate catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1m32, PDBe:1m32, PDBj:1m32
PDBsum1m32
PubMed12403617
UniProtP96060|PHNW_SALTY 2-aminoethylphosphonate--pyruvate transaminase (Gene Name=phnW)

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