Structure of PDB 1m1j Chain E Binding Site BS01

Receptor Information

>1m1j Chain E (length=401) Species: 9031 (Gallus gallus)

IYPDAGGCKHPLDELGVLCPTGCELQTTLLKQEKTVKPVLRDLKDRVAKF
SDTSTTMYQYVNMIDNKLVKTQKQRKDNDIILSEYNTEMELHYNYIKDNL
DNNIPSSLRVLRAVIDSLHKKIQKLENAIATQTDYCRSPCVASCNIPVVS
GRECEDIYRKGGETSEMYIIQPDPFTTPYRVYCDMETDNGGWTLIQNRQD
GSVNFGRAWDEYKRGFGNIAKSGGKKYCDTPGEYWLGNDKISQLTKIGPT
KVLIEMEDWNGDKVSALYGGFTIHNEGNKYQLSVSNYKGNAGNALMEGAS
QLYGENRTMTIHNGMYFSTYDRDNDGWLTTDPRKQCSKEDGGGWWYNRCH
AANPNGRYYWGGTYSWDMAKHGTDDGIVWMNWKGSWYSMKKMSMKIKPYF
P

Ligand information

>1m1j Chain J (length=4)

GHRP

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1m1j Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): L364 M371 W389 E401 D402 R410 C411 H412 T435 D436 M442
• Binding residue (residue number reindexed from 1): L302 M309 W327 E339 D340 R348 C349 H350 T373 D374 M380

Gene Ontology

Molecular Function

• GO:0005102 signaling receptor binding
• GO:0030674 protein-macromolecule adaptor activity
• GO:0046872 metal ion binding

Biological Process

• GO:0007160 cell-matrix adhesion
• GO:0007596 blood coagulation
• GO:0030168 platelet activation
• GO:0051258 protein polymerization
• GO:0070527 platelet aggregation
• GO:0072378 blood coagulation, fibrin clot formation

Cellular Component

• GO:0005576 extracellular region
• GO:0005577 fibrinogen complex
• GO:0005615 extracellular space
• GO:0062023 collagen-containing extracellular matrix

External links

• PDB: RCSB:1m1j, PDBe:1m1j, PDBj:1m1j
• PDBsum: 1m1j
• PubMed: 11601975
• UniProt: Q02020|FIBB_CHICK Fibrinogen beta chain (Fragment) (Gene Name=FGB)