Structure of PDB 1lwu Chain E Binding Site BS01

Receptor Information
>1lwu Chain E (length=315) Species: 7757 (Petromyzon marinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQKEIENRYKEVKIRIESTVAGSLRSMKSVLEHLRAKMQRMEEAIKTQKE
LCSAPCTVNCRVPVVSGMHCEDIYRNGGRTSEAYYIQPDLFSEPYKVFCD
MESHGGGWTVVQNRVDGSSNFARDWNTYKAEFGNIAFGNGKSICNIPGEY
WLGTKTVHQLTKQHTQQVLFDMSDWEGSSVYAQYASFRPENEAQGYRLWV
EDYSGNAGNALLEGATQLMGDNRTMTIHNGMQFSTFDRDNDNWNPGDPTK
HCSREDAGGWWYNRCHAANPNGRYYWGGIYTKEQADYGTDDGVVWMNWKG
SWYSMRQMAMKLRPK
Ligand information
Receptor-Ligand Complex Structure
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PDB1lwu Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		L380 N384 M387 T388 W405 E417 D418 R426 C427 H428 T451 D452 M458
Binding residue
(residue number reindexed from 1)		L218 N222 M225 T226 W243 E255 D256 R264 C265 H266 T289 D290 M296
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1lwu, PDBe:1lwu, PDBj:1lwu
PDBsum1lwu
PubMed12162736
UniProtP02678|FIBB_PETMA Fibrinogen beta chain (Fragments)

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