Structure of PDB 1ltj Chain E Binding Site BS01
Receptor Information
>1ltj Chain E (length=294) Species:
9606
(Homo sapiens) [
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LRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEI
IRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGR
KWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEM
EDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGEN
RTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNG
RYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFF
Ligand information
>1ltj Chain J (length=4) [
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GHRP
Receptor-Ligand Complex Structure
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PDB
1ltj
2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
N364 M367 W385 E397 R406 C407 H408 T431 D432 M438
Binding residue
(residue number reindexed from 1)
N200 M203 W221 E233 R242 C243 H244 T267 D268 M274
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005102
signaling receptor binding
Biological Process
GO:0007596
blood coagulation
GO:0030168
platelet activation
GO:0051258
protein polymerization
Cellular Component
GO:0005577
fibrinogen complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1ltj
,
PDBe:1ltj
,
PDBj:1ltj
PDBsum
1ltj
PubMed
12356313
UniProt
P02675
|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)
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