Structure of PDB 1lau Chain E Binding Site BS01

Receptor Information
>1lau Chain E (length=228) Species: 10298 (Human alphaherpesvirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDWTTFRRVFLIDDAWRPLMEPELANPLTAHLLAEYNRRCQTEEVLPPRE
DVFSWTRYCTPDEVRVVIIGQDPYHHPGQAHGLAFSVRANVPPPPSLRNV
LAAVKNCYPEARMSGHGCLEKWARDGVLLLNTTLTVKRGAAASHSRIGWD
RFVGGVIRRLAARRPGLVFMLWGTHAQNAIRPDPRVHCVLKFSHPSPLSK
VPFGTCQHFLVANRYLETRSISPIDWSV
Ligand information
Receptor-Ligand Complex Structure
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PDB1lau The structural basis of specific base-excision repair by uracil-DNA glycosylase.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D88 P89 Y90 H91 H92 P111 S112 P213 L214
Binding residue
(residue number reindexed from 1)		D72 P73 Y74 H75 H76 P95 S96 P197 L198
Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Gene Ontology
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1lau, PDBe:1lau, PDBj:1lau
PDBsum1lau
PubMed7845459
UniProtP10186|UNG_HHV11 Uracil-DNA glycosylase (Gene Name=UL2)

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