Structure of PDB 1kyo Chain E Binding Site BS01

Receptor Information

>1kyo Chain E (length=185) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KSTYRTPNFDDVLKENNDADKGRSYAYFMVGAMGLLSSAGAKSTVETFIS
SMTATADVLAMAKVEVNLAAIPLGKNVVVKWQGKPVFIRHRTPHEIQEAN
SVDMSALKDPQTDADRVKDPQWLIMLGICTHLGCVPIGEAGDFGGWFCPC
HGSHYDISGRIRKGPAPLNLEIPAYEFDGDKVIVG

Ligand information

InChI=1S/2Fe.2S

NIXDOXVAJZFRNF-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04	[Fe]1S[Fe]S1
CACTVS 3.341 OpenEye OEToolkits 1.5.0	S1[Fe]S[Fe]1

Formula

Fe2 S2

Name

FE2/S2 (INORGANIC) CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

1kyo Chain E Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1kyo Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c.
Resolution	2.97 Å
Binding residue (original residue number in PDB)	C159 H161 L162 C164 C178 C180 H181 S183
Binding residue (residue number reindexed from 1)	C129 H131 L132 C134 C148 C150 H151 S153
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H181
Catalytic site (residue number reindexed from 1)	H151
Enzyme Commision number	7.1.1.8: quinol--cytochrome-c reductase.

Gene Ontology

	Molecular Function
GO:0008121	ubiquinol-cytochrome-c reductase activity
GO:0051537	2 iron, 2 sulfur cluster binding

	Cellular Component
GO:0016020	membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1kyo, PDBe:1kyo, PDBj:1kyo
PDBsum	1kyo
PubMed	11880631
UniProt	P08067\|UCRI_YEAST Cytochrome b-c1 complex subunit Rieske, mitochondrial (Gene Name=RIP1)

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