Structure of PDB 1jdi Chain E Binding Site BS01

Receptor Information
>1jdi Chain E (length=223) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSI
MTADDMVVVSIETGEVVEGAKKPSSDTPTHRLLYQAFPSIGGIVHTHSRH
ATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIV
ETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFC
RQLAPQLPDMQQTLLNKHYLRKH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1jdi Chain E Residue 305 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1jdi The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H95 H97 H171
Binding residue
(residue number reindexed from 1)		H95 H97 H171
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D76 H95 H97 T116 D120 H171
Catalytic site (residue number reindexed from 1) D76 H95 H97 T116 D120 H171
Enzyme Commision number 5.1.3.4: L-ribulose-5-phosphate 4-epimerase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0008742 L-ribulose-phosphate 4-epimerase activity
GO:0016832 aldehyde-lyase activity
GO:0016853 isomerase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0005996 monosaccharide metabolic process
GO:0019323 pentose catabolic process
GO:0019324 L-lyxose metabolic process
GO:0019568 arabinose catabolic process
GO:0019569 L-arabinose catabolic process to xylulose 5-phosphate
GO:0019572 L-arabinose catabolic process
Cellular Component
GO:0005829 cytosol
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1jdi, PDBe:1jdi, PDBj:1jdi
PDBsum1jdi
PubMed11732895
UniProtP08203|ARAD_ECOLI L-ribulose-5-phosphate 4-epimerase AraD (Gene Name=araD)

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