Structure of PDB 1im3 Chain E Binding Site BS01

Receptor Information
>1im3 Chain E (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>1im3 Chain G (length=9) Species: 11927 (Human T-cell lymphotrophic virus type 1 (Caribbean isolate)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LLFGYPVYV
Receptor-Ligand Complex Structure
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PDB1im3 Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 T73 D77 Y84 R97 Y99 Y116 T143 K146 W147 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 T73 D77 Y84 R97 Y99 Y116 T143 K146 W147 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1im3, PDBe:1im3, PDBj:1im3
PDBsum1im3
PubMed11391001
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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