Structure of PDB 1gmo Chain E Binding Site BS01

Receptor Information
>1gmo Chain E (length=173) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCADRCTRNKGLPFTCKA
FVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSY
KGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG
PWCFTSNPEVRYEVCDIPQCSEV
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1gmo Chain E Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1gmo Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor
Resolution3.0 Å
Binding residue
(original residue number in PDB)		I129 I130 G133 S135
Binding residue
(residue number reindexed from 1)		I93 I94 G97 S99
Annotation score3
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1gmo, PDBe:1gmo, PDBj:1gmo
PDBsum1gmo
PubMed11597998
UniProtP14210|HGF_HUMAN Hepatocyte growth factor (Gene Name=HGF)

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