Structure of PDB 1fka Chain E Binding Site BS01

Receptor Information
>1fka Chain E (length=157) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPETDFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPE
VPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGV
IAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVER
LRKGEAH
Ligand information
>1fka Chain A (length=1479) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguacuccguggucagcggcggacgggu
gaguaacgcgugggugaccuacccggaagagggggacaacccggggaaac
ucgggcuaaucccccauguggacccgccccuugggguguguccaaagggc
uuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggggua
auggcccaccaaggcgacgacggguagccggucugagaggauggccggcc
acaggggcacugagacacgggccccacuccuacgggaggcagcaguuagg
aaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaa
gaagcccuucgggguguaaacuccugaacccgggacgaaacccccgacga
ggggacugacgguaccgggguaauagcgccggccaacuccgugccagcag
ccgcgguaauacggagggcgcgagcguuacccgcguaaagggcguguagg
cggccuggggcgucccaugugaaagaccacggcucaaccgugggggagcg
ugggauacgcucaggcuagacggugggagagggugguggaauucccggag
uagcggugaaaugcgcagauaccgggaggaacgccgauggcgaaggcagc
caccugguccacccgugacgcugaggcgcgaaagcguggggagcaaaccg
gauuaacccggguaguccacgcccuaaacgaugcgcgcuaggucucuggg
ucuccugggggccgaagcuaacgcguuaagcgcgccgccuggggaguacg
gccgcaaggcugaaacucaaaggaauugacgggggcccgcacaagcggug
gagcaugugguuuaauucgcgaagaaccuuaccaggccuugacaugcuag
ggaacccgggugaaagccuggggugcccgcgagggagcccuagcacaggu
gcugggccgucgucagcucgugccgugagguguuggguuaagucccgcaa
cgagcgcaacccccgccguuaguugccagcgguucggccgggcacucuaa
cgggacugcccgcgaaagcgggaggaaggaggggacgacgucuggucagc
auggcccuuacggccugggcgacacacgugcuacaaugcccuacaaagcg
augccacccggcaacggggagcuaaucgcaaaaaggugggcccaguucgg
auuggggucugcaacccgaccccaugaagccggaaucgcuaguaaucgcg
gaucagccaugccgcggugaauacguucccgggccuuguacacaccgccc
gucacgccaugggagcgggcucuacccgaagucgccgggagccuacgggc
aggcgccgaggguagggcccgugacuggggcgaagucguaacaagguagc
uguaccggaaggugcggcuggaucaccuc
....<<<<<...((((>>>>>.<<<..<<<<<..<<<<<<...<.....<
...<..<<..<<<.<<<<<<<<<<..>>>>>>>>>>.>>>>>......<<
.......<<<<<<<...<<...<<<<<<<.<<<<<....<<<<<......
>>>>>.....>>>>>.....<<<.<<<<<....>>>>>.>>>....<<<<
...>>>>.>>>>>>>..>>.>>>>>>>.<<..<.<<<..<<<<<<<<.<.
...>>>>>>>>>>>>...>...>>..<<<<<<<......>>>...>>>>.
>>.<<<<<.<<.......>>>>>>>.<<<<....>>>>...>..>...>.
.....<<<....<<.<......>.>>..>>>....>>>>>>..<<<<...
...<<<<....>>>>.....>>>>....<<<<.<........<<<.....
>.>>..........>>>>>......<<<<<(((...<<<<<........)
)).........>>>>>>>>>>..>>>>>.>>><<.......<<<<...<<
<.<<<<<<.<<<<<<<<<<<......<<<<<<.....>>>>>>....>>>
>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<..
<.<<<......>>>......>>>>>>>>...........<<....>>.>>
>>>>>..>>>>.>>>>...>>>...>>>>....<<<<.<<..<<..<<<<
<......>>>>.>.>>>>>>>>..........<<<<<<<.<<<<<<<<<<
...>>>>>>>>>>...............>>>>>>>.>>..<........<
<<<....>>>>.....>...))))....<<<.<<<<<......<<<<<..
.<<<<<<<<<<....................<<<<<<.......<.<<<<
<<..<<<<<<<....>>>>>>>...<........>..>>>>>>.>..<<.
.<...<.<..<....<<<<<<<<<....>>>..<<<<......>>>>..>
>>>>>.....<<<<.<<<<<<<...<<..<<<.....>>>>>....>>>>
>>>.....<<<<......>>>>........>>>>.....>....>>....
...>.>>.....>>>>>>...>>.>>>>>>>>.....<<<<.<<......
..<...<<<......>.>>..>.............>>>>>>.........
..<<<<<<<........>>>>>>>...........>>>>>....<<<<<<
<..........>>>>>>>.............>>>>>>>>..........<
<.<.<<<..<.<<.<<<<<<<<<<<<....<.<<<......<<<..>>>.
..>>>.>...>>>>>>>>>>>>..>>>..>>>..>.>>.........<<<
<<<<<<....>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1fka Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
G85 R126
Binding residue
(residue number reindexed from 1)
G85 R126
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1fka, PDBe:1fka, PDBj:1fka
PDBsum1fka
PubMed11007480
UniProtQ5SHQ5|RS5_THET8 Small ribosomal subunit protein uS5 (Gene Name=rpsE)

[Back to BioLiP]