Structure of PDB 1epm Chain E Binding Site BS01

Receptor Information
>1epm Chain E (length=330) Species: 5116 (Cryphonectria parasitica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTA
SEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLT
VTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKA
SLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTST
GYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGG
YVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGI
GINIFGDVALKAAFVVFNGATTPTLGFASK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1epm A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		D12 D30 D32 G34 I73 Y75 G76 D77 D215 G217 T218 T219 L220 F275 F284 I299
Binding residue
(residue number reindexed from 1)		D15 D33 D35 G37 I77 Y79 G80 D81 D219 G221 T222 T223 L224 F280 F291 I302
Enzymatic activity
Enzyme Commision number 3.4.23.22: endothiapepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1epm, PDBe:1epm, PDBj:1epm
PDBsum1epm
PubMed7703859
UniProtP11838|CARP_CRYPA Endothiapepsin (Gene Name=EAPA)

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