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BioLiP

Structure of PDB 1dm5 Chain E Binding Site BS01

Receptor Information
>1dm5 Chain E (length=315) Species: 6087 (Hydra vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQI
KTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGL
GTDKNALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLL
VSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSY
PQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAE
RLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADD
CSGDYKDLLLQITGH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1dm5 Chain E Residue 1125 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1dm5 Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization.
Resolution1.93 Å
Binding residue
(original residue number in PDB)		M98 K99 G100
Binding residue
(residue number reindexed from 1)		M97 K98 G99
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1dm5, PDBe:1dm5, PDBj:1dm5
PDBsum1dm5
PubMed10704197
UniProtP26256|ANX12_HYDVU Annexin-B12 (Gene Name=ANXB12)

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