Structure of PDB 1apv Chain E Binding Site BS01

Receptor Information

>1apv Chain E (length=323) Species: 5079 (Penicillium janthinellum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AASGVATNTPTANDEEYITPVTIGGTTLNLNFDTGSADLWVFSTELPASQ
QSGHSVYNPSATGKELSGYTWSISYGDGSSASGNVFTDSVTVGGVTAHGQ
AVQAAQQISAQFQQDTNNDGLLGLAFSSINTVQPQSQTTFFDTVKSSLAQ
PLFAVALKHQQPGVYDFGFIDSSKYTGSLTYTGVDNSQGFWSFNVDSYTA
GSQSGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSNAGGYVFDCS
TNLPDFSVSISGYTATVPGSLINYGPSGDGSTCLGGIQSNSGIGFSIFGD
IFLKSQYVVFDSDGPQLGFAPQA

Ligand information

>1apv Chain I (length=4) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

VVVL

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1apv Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides.
Resolution	1.8 Å
Binding residue (original residue number in PDB)	E15 D33 G35 Y75 G76 D77 D213 G215 T216 T217
Binding residue (residue number reindexed from 1)	E15 D33 G35 Y75 G76 D77 D213 G215 T216 T217

Enzymatic activity

Enzyme Commision number

3.4.23.20: penicillopepsin.

Gene Ontology

	Molecular Function
GO:0004190	aspartic-type endopeptidase activity

	Biological Process
GO:0006508	proteolysis

	Cellular Component
GO:0005576	extracellular region

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Cellular Component

External links

PDB	RCSB:1apv, PDBe:1apv, PDBj:1apv
PDBsum	1apv
PubMed	1567842
UniProt	P00798\|PEPA1_PENJA Penicillopepsin-1

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