Structure of PDB 1apt Chain E Binding Site BS01

Receptor Information

>1apt Chain E (length=323) Species: 5079 (Penicillium janthinellum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AASGVATNTPTANDEEYITPVTIGGTTLNLNFDTGSADLWVFSTELPASQ
QSGHSVYNPSATGKELSGYTWSISYGDGSSASGNVFTDSVTVGGVTAHGQ
AVQAAQQISAQFQQDTNNDGLLGLAFSSINTVQPQSQTTFFDTVKSSLAQ
PLFAVALKHQQPGVYDFGFIDSSKYTGSLTYTGVDNSQGFWSFNVDSYTA
GSQSGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSNAGGYVFDCS
TNLPDFSVSISGYTATVPGSLINYGPSGDGSTCLGGIQSNSGIGFSIFGD
IFLKSQYVVFDSDGPQLGFAPQA

Ligand information

>1apt Chain I (length=4) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

VVVK

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1apt Conformational Flexibility in the Active Sites of Aspartyl Proteinases Revealed by a Pepstatin Fragment Binding to Penicillopepsin
Resolution	1.8 Å
Binding residue (original residue number in PDB)	D33 Y75 G76 D77 D213 G215 T216 T217
Binding residue (residue number reindexed from 1)	D33 Y75 G76 D77 D213 G215 T216 T217

Enzymatic activity

Enzyme Commision number

3.4.23.20: penicillopepsin.

Gene Ontology

	Molecular Function
GO:0004190	aspartic-type endopeptidase activity

	Biological Process
GO:0006508	proteolysis

	Cellular Component
GO:0005576	extracellular region

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Cellular Component

External links

PDB	RCSB:1apt, PDBe:1apt, PDBj:1apt
PDBsum	1apt
PubMed
UniProt	P00798\|PEPA1_PENJA Penicillopepsin-1

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