Structure of PDB 8b6h Chain Db Binding Site BS01

Receptor Information
>8b6h Chain Db (length=604) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MWGNLWTEASYQLNFNIGFSSLRSDVLIHLAQWQYWWWFWFALIWSFYYF
IILKVARFRVLKMRPKISTSYRPHGKWGDFLACIIPLIWCINILTNSNLI
LRLIEWQNESSLFTVRVRARQWYWIYKFELKNFTDILSTPKNIGNNRWQI
NTFGELQTADDYLHVLQLRSQNKWVKNYWNRSLQETGKTNKAHVISPQEQ
LRLSLINQYKSLNLSSSIKHNAPFINRDLYVFDDLFSYNLGDITTKKSLF
NDKNSFLTSYSYLNNNSWNNNEFDLIDNLPFTTLFDNNDLFNNYKSFFQD
SIFNSPKKQLSSDSKQLFKHIIYRSIKNNIIQDYTKLVKHEDFDEYSRWI
KRSPGEVLPLRIIKYPLGLETIHNNIFENTNNEGNVELFRLRFNSNSSKM
QHKLVQDTIYLTLKQKRYNRKKVVAPQIKYYKDDNGNKTDLVKYTGKPYL
SNDKLLKQSIYDQTTQYKLIKKNKKRGELIPVTLARRILRTKKTLVLPAH
VNITLITNSYDIVHSWFIPGLGIKLDCVPGRSTHHTFFIDNVGFYYGQCA
EICGRYHHHMPIRVCALPFEHFLLWWNTFGLPKMLNTVSRKRFETHYELR
KYSW
Ligand information
Ligand IDCUA
InChIInChI=1S/2Cu
InChIKeyALKZAGKDWUSJED-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cu][Cu]
FormulaCu2
NameDINUCLEAR COPPER ION
ChEMBL
DrugBank
ZINC
PDB chain8b6h Chain Db Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b6h Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		H514 C549 C553 H557
Binding residue
(residue number reindexed from 1)		H514 C549 C553 H557
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b6h, PDBe:8b6h, PDBj:8b6h
PDBsum8b6h
PubMed36949187
UniProtQ950Y9

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