Structure of PDB 6hiy Chain DZ Binding Site BS01

Receptor Information

>6hiy Chain DZ (length=82) Species: 5702 (Trypanosoma brucei brucei)

MKYADLELTTRGEFPHGMKEPAFVKKLDQNIPWYFSTYRSMYHWPITGDN
WSDLNEAEKHHDLHMFYTLAWWKLGEGIFGVD

Ligand information

>6hiy Chain CA (length=478)

uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuaaaaagg
uauuguugcccaccaauuuuuauaauaaaaauaacgugcaguaauuaaua
uauuuauaaaaauauauuuuuuuuuuuu

....................<<<.......<<<<..............<.
..>..........................................<<...
.<<...<<<.......>>>..>>.......>>........<<....>>..
..................................................
.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.>>....<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<
<<<<<....>>>>>>>>>..........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6hiy Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
• Resolution: 3.27 Å
• Binding residue (original residue number in PDB): N39 I40 Y43
• Binding residue (residue number reindexed from 1): N30 I31 Y34

Gene Ontology

Cellular Component

• GO:0005739 mitochondrion
• GO:0005763 mitochondrial small ribosomal subunit

External links

• PDB: RCSB:6hiy, PDBe:6hiy, PDBj:6hiy
• PDBsum: 6hiy
• PubMed: 30213880
• UniProt: Q587C4