Structure of PDB 7pua Chain DX Binding Site BS01

Receptor Information

>7pua Chain DX (length=129) Species: 5702 (Trypanosoma brucei brucei)

QGFHEKAQKWREEYLLDRHRALADSLRAYVEFSTSKRVEPWDARFKPFDR
IEKDGVYVLMRYMMEEKLQLCNYHHRPVKRLFCNIGLMGPQITTKARWKP
YRFATNPAGTSKAERMYQRDKTVYTHGHN

Ligand information

>7pua Chain CA (length=501)

uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaaauaaauuaaauuagu
cagaaauggaugccagccguugcgguaauuucuaugcuuuuaaauauuau
acaaaauuguuaagugcugauuuaaccaauaaaaauauaaauaauuuuac
cauuagguauuuuauucauauaauuaauaggauaauauuuguaguuuuug
auaccaugauaaggauuauaaauugaaaguguuaauaucauaaucaaaau
uuauuauuuauauuaaauauguauguguagauaaaauaagacccaccaau
uuuuauaauaaaaauaacgugcaguaauuaauauauuuauaaaaauauau
u

..............................<<<<<....<........<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
.......................................>.......<<<
.....<<<<<.....<<....>>.......>>>>>>>>.....>.>>>>.
.....<<<<<<<<<<....>>>>>>.>>>>..................<<
<....>>>..<<<<<...................................
......<.<<<<...................>>.>>>.............
..............................>>>>>........<<<..<<
<<<<.....>>>>>>...>>>........<<<<<<<<<....>>>>>>>>
>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7pua Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
• Resolution: 3.6 Å
• Binding residue (original residue number in PDB): R115 K118 T132 R136 W137 R141 Y156 K160 V162 Y163 T164 H165
• Binding residue (residue number reindexed from 1): R76 K79 T93 R97 W98 R102 Y117 K121 V123 Y124 T125 H126

Gene Ontology

Cellular Component

• GO:0005739 mitochondrion

External links

• PDB: RCSB:7pua, PDBe:7pua, PDBj:7pua
• PDBsum: 7pua
• PubMed: 35042777
• UniProt: Q383G5