Structure of PDB 6hiv Chain DX Binding Site BS01

Receptor Information
>6hiv Chain DX (length=141) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WAKPKKRPKVGQGFHEKAQKWREEYLLDRHRALADSLRAYVEFSTSKRVE
PWDARFKPFDRIEKDGVYVLMRYMMEEKLQLCNYHHRPVKRLFCNIGLMG
PQITTKARWKPYRFATNPAGTSKAERMYQRDKTVYTHGHND
Ligand information
>6hiv Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
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....................<<<.......<<<<..............<.
..>..........................................<<...
.<<...<<<.......>>>..>>.......>>........<<....>>..
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.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.<<<<<............................................
..................................................
.....................>>>>>..................>>....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)
W29 H114 R115 K118 T132 R136 W137 P139 Y140 R141 F142 Y156 Y163 H165
Binding residue
(residue number reindexed from 1)
W1 H86 R87 K90 T104 R108 W109 P111 Y112 R113 F114 Y128 Y135 H137
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ383G5

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