Structure of PDB 6zqg Chain DW Binding Site BS01

Receptor Information
>6zqg Chain DW (length=129) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRSSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFE
YIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGY
VILTTSAGIMDHEEARRKHVSGKILGFVY
Ligand information
>6zqg Chain D3 (length=1387) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuauguugcaguuaaaaagcucguaguugaacuuugggcccgguuggcc
ggucggauuuccaacggggccuuuccuucuggcuaaccuugaguccuugu
ggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaa
gcaggcguauugcucgaauauauuagcauggaauaauagaauaggacguu
ugguucuauuuuguugguuucuaggaccaucguaaugauuaauagggacg
gucgggggcaucaguauucaauugucagaggugaaauucuuggauuuauu
gaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaa
gaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaac
cauaaacuaugccgacuagggaucgggugguguuuuuuuaaugacccacu
cggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaugguc
gcaaggcuaaagacggaagggcaccaccaggaguggagccugcggcuuac
acgcgcgcuacacugacggagccagcgagucuaaccuuggccgagagguc
uugguaaucuugugaaacuccgucgugcuggggauagagcauuguaauua
uugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguu
gauuacgucccugcccuuuguacacaccgcccgucgcuaguaccggaacu
aauuccguaggugaaccugcggaaggaucauuaaaga
<..<<<<<.......>>>>>.><..<<<<<<...<.<..........<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<..................<.....<<
.<<<.....>>>.>>......>.........<<<<<..<<....>>..>>
>>><.<.<<<<<<......((((((..<<<....>>>.............
.>>>>>>.>...>...<<<<..<<<.....>>>.>>>>....>>>...>>
>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<
.....>>>..>>>.......>.>.....<<<<<.................
...>>.>>>......<<..<...........>..>>.........<<<<<
<.......<<<....>>>..................>>>>>>..>>>>>>
.>.......<<<[[.....<.<<...<<<.<<....<<<<<<.<<<<<..
..........>>>>>.>>>>>>....<<<<<<.........<<<......
.>>>.........>>>>>>...<<<<<.<<.......<<...<.......
>..<<<.....>>>....>>......>>.>>..>>>.........<<<..
..<<<<<.......))))))..>>>>>...>>>.....>>....<<<<<<
.<<...<<<<..<<..<<<<<<.<...<<<..(...>>>......>.>>>
>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>...
>>.>....<<<<<<<...<...<<<<..)......>>>>...>>>>>>>>
..........<<<.<<.<<<..<<<<<<<<.<<<........>>>>>>>>
>>>..>>>...<<..]]>>...>>.....>>>.>>>..............
...........<<<<<<<<<<<<..<<.<<<<<...<<<.<<<<......
.>>>>.>>>.....<<<<<<<......<<.....<<..<<<<....>>>>
..>>....>>.......>>>>>>>...........<<<<<<.........
.>>>>>>...........>>>>>....<<<<<<<.........>>>>>>>
......>>...>>>>>>>............>>>>>..<<<<.<<>>.>>>
>.<<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6zqg 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
T2 R3 V6 N12 N15 N16 E18 K19 K22 R28 S31 K32 H56 R57 L69 N70 V74 I75 S76 N80 K82 T105 T106 S107 R118 H120
Binding residue
(residue number reindexed from 1)
T1 R2 V5 N11 N14 N15 E17 K18 K21 R27 S30 K31 H55 R56 L68 N69 V73 I74 S75 N79 K81 T104 T105 S106 R117 H119
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6zqg, PDBe:6zqg, PDBj:6zqg
PDBsum6zqg
PubMed32943521
UniProtP0C0W1|RS22A_YEAST Small ribosomal subunit protein uS8A (Gene Name=RPS22A)

[Back to BioLiP]