Structure of PDB 4bts Chain DW Binding Site BS01

Receptor Information
>4bts Chain DW (length=259) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARGPKKHLKRINAPKSWMLNKLGGIWATRPSQGPHKLRESLPLSVLLKER
LNYALNGRDVTLILNDKEQNVFVDGKVRRDKGYPTGLMDVVRIEKTDQSF
RILYDTKGRFVLKSLSKEEAKYKLLKVTAKAIGPNQIPYIVTHDSRTIRF
PNPEIKIGDTLKYDLVNNKIENFAHLESGNVCYIQQGNNIGRVGIIQHIE
KHQGSFDICHVKDAKGNAFATRLGNIFVLGQGKKSWIELPSGDGVRETIL
EERKRKFSY
Ligand information
>4bts Chain DA (length=1717) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugauccugccaguuacauaugcuugucuuaaauauuaaccca
ugcaugugccaguucaguauugaacagcgaaacugcgaauggcucauuaa
aacaguuauaguuuauuugauaauuaaagauuacauggauaaccgagcua
auuguugggcuaauacaugcuuaaaauuccguguccugcgaccggaacgu
auuuauuagauauuagaccaaucgcagcaaugugauugagaugaaucaaa
guaacugaucggaucgagguuuaccucgauaaaucaucuaaguuucugcc
cuaucagcucucgaugguaguguauuggacuaccauggcagucacgggua
acggagaauuaggguucgauuccggagaaggagccugagaaacggcuacu
acaacuacgguucggcagcagggaagaaaauuggccaauccuaauucagg
gagccagugacaagaaauagcaagcugggaaacuuacguuucuacggcau
ugaaaugagaacaguguaaaucucuuagcgaggaacaauuggagggcaag
ucauggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugcaguuaaaaagcucguaguugaacuucuguucagguucauuuc
gauucgucgugugaaacuggacauacguuugcguaaacauuuuacuguga
aaaaauuagaguguuccaggcagguuuuagcccgaauacauuagcaugga
auaauggaauaggacuaaguccauuuuauugguucuuggauuugguaaug
auuaauagggacaguugggggcauuaguauuuaauagucagaggugaaau
ucuuggauuuauuaaggacuaacuaaugcgaaagcauuugccaaagaugu
uuucauuaaucaagaacgaaaguuaggggaucaaagacgaucagauaccg
ucguagucuuaacuauaaacuauaccgacucgggaucggcuggaauaaau
guccagucggcaccguaugagaaaucaaagucuuuggguucugggggaag
uaugguacgcaagucugaaacuuaaaggaauugacggaacagcacaccag
aaguggaaccugcggcuuaauuugacucaacacggggaaacucacgagcg
caagacagagaagggauugacagauugagagcucuuucuugauucuuugg
gugguggugcauggccguucuuaguugguggagugauuugucugguuaau
uccguuaacgaacgagaccuuaaccugcuaacuagucugcuuguaaauaa
cagguuguacuucuuagagggacuauugugcaauaagccaauggaaguuu
aaggcaauaacaggucugugaugccccuagacgugcucggccgcacgcgc
guuacaaugacuggcgcaaaaaguauuuccuguccugggaagguacgggu
aaucuuauuaauaccagucguguuagggauaguucuuuggaauuguggau
cuugaacgaggaauuucuaguaagugcaagucaucagcuugcguugauua
ugucccugccguuuguacacaccgcccgucgcuuguaguaacgaaugguc
uggugaaccuucuggacugcgacagcaauguugcggaaaaauaaguaaac
ccuaccauuuggaacaacaagaagucguaacaagguaucuguaggugaac
cugcagauggaucauua
...<<<<<.{.[[[[>>>>><.<.<<<<<<...<<<<.........<<<.
<<<..<<....<<...<<........>>...>>.>>......<<..<...
..<<<..<<..<<....<<<<..............<<.....<<.<<<..
...>>>.>>......>>.........<<<<<.<<<....>>>>>>>>.<.
..<<<<<........((((((..<<<....>>>......<......>..>
>>>>.....>...<<<<<<....>>>>>>...>>>>...>>>>..>>>.<
<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>..
.<<<<<<<<....>>>>...>>>>>>>.<<.<<<..........>>>.>>
..<<<....>>>.....>>>>>>.........<<<....<<<.....>>>
..>>>......>>>>.....<<<<<<<.<<<<<....>>>>>..>>>>.>
>>..........<<.........>>.............<<<<<((.....
...<<<.....<<..))>>.......>>>..>>>>>..>>>>>>.>.>..
.......<<<[[.....<.<<...<<<.<<....<<<<<<<.<<<<<..<
<<<..>>>>.>>>>>.>>>>>>>...<<<<<..>>>>>...<<<<<<<<.
......<<...<.......>..<<<....>>>....>>......>>>>>.
.>>>.........<<<<<<<<<<.....))))))..>>>>>>>>>>....
.>>....<<<<<<.<<...<<<<..<<..<<<<<<<<...<<<......>
>>......>>>>>>>>..>>.......<<....>>...>>>>...>>>>>
.>>>...>>>...>>.>...<<<<<<<<...<...<<<<.........>>
>>...>>>>>>>>>.........<<<.<<.<<<..<<<<<<<<<......
.>>>>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<...
...<<.<<....>>>>....>>>..]]]].}<<<<<.<<<.<<<.<<.<<
<<<<..<<<.<<<<<.......<<........>>..........<<<<<<
.....<<<<<<.......<<.<<<........>>>.>>.....>>>>>>.
..<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<.....
.>>>...>>.>>>....<<<<<.<<..<<<<..<<<..<<<<<<.....>
>>>>>...>>>..>>>>.>>....<<<<.<<.....>>>>>>.......>
>>>>....>>>.>>>...>.>>>>>>>......>>>>>>....>.>>>>.
>>>.....<<<<<<.......<<.....<<<<<<<<....>>>.>>>>>.
...>>........>>>>>>...........<<.<<<..........>>>.
>>..........>>>>>>....<<<<<<<<.......>>>>>>>>.....
.>>...>>>.>>>>>>.>>....<..<<.<.<<<<<.<<..<<<<<<<<.
.<<<..<<.<..<...<<<<<<<<....>>>>>>>>...>..>.>>..>>
>..>>>>>>>>..>>.>>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bts The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Resolution3.703 Å
Binding residue
(original residue number in PDB)
R3 G4 P5 K7 H8 K10 I12 M19 K22 L23 I26 W27 A28 T29 R30 Q33 G34 K37 L38 N57 G58 R59 N66 K68 R79 K108 R110 K131 I133 G134 N136 Q137 S146 R147 T148 R150 N189 H203 Q204 A221 T222 R223 K257
Binding residue
(residue number reindexed from 1)
R2 G3 P4 K6 H7 K9 I11 M18 K21 L22 I25 W26 A27 T28 R29 Q32 G33 K36 L37 N56 G57 R58 N65 K67 R78 K107 R109 K130 I132 G133 N135 Q136 S145 R146 T147 R149 N188 H202 Q203 A220 T221 R222 K256
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4bts, PDBe:4bts, PDBj:4bts
PDBsum4bts
PubMed23851459
UniProtE6PBS2

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