Structure of PDB 6hiv Chain DS Binding Site BS01

Receptor Information
>6hiv Chain DS (length=238) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRWSSVWPNMRYGSMFLSYSVGRKLPMKGVNWVTRDSNRLLNFSNRYSAV
ISDIDVKRTEEELNVALSDIRWNDHRRIYWKCSFCGSSYRKNVSVRTKYH
AGCNFCKKKYPSEVRGEQHGSPPVSQAAPELTEQLVDNGKRDNLATLAVT
SKFYAEWTCRGCGGSYRSTIRSRTGQVEAGQCTLHPDIVAWSAYCPSCSW
RPNMVPIAEEVSRSGQFLGLERSMEELGPIPRRKRLAC
Ligand information
>6hiv Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
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....................<<<.......<<<<..............<.
..>..........................................<<...
.<<...<<<.......>>>..>>.......>>........<<....>>..
..................................................
.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.<<<<<............................................
..................................................
.....................>>>>>..................>>....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)		S17 R18 W19 S20 S21 W23 N25 R27 G29 S30 M31 F32 L33 Y35 S36 V37 G38 R39 K40 L41 P42 M43 V46 W48 H91 R93 K107 N108 S110 V111 K114 Y115 N120 K123
Binding residue
(residue number reindexed from 1)		S1 R2 W3 S4 S5 W7 N9 R11 G13 S14 M15 F16 L17 Y19 S20 V21 G22 R23 K24 L25 P26 M27 V30 W32 H75 R77 K91 N92 S94 V95 K98 Y99 N104 K107
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ388L7

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