Structure of PDB 8c3a Chain DQ Binding Site BS01

Receptor Information
>8c3a Chain DQ (length=54) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HENVWFSHPRNFGKGSRQCRHCSSHSGLIRKYGLDLCRQCFREKAADIGF
NKYR
Ligand information
>8c3a Chain CM (length=1765) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguaccuuacuacuuggauaaccgu
gguaauucuagagcuaauacaugcuuaaaaucccgacuguuuggaaggga
uguauuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucau
aauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaau
uucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuca
acggguaacggggaauaaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccga
cacggggagguagugacaauaaauaacgauacagggcccuuuugggucuu
guaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaaaagcguauau
uaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcugg
ccgguccauaugcguacuggacccagccgagccuuuccuucuggguagcc
auuuauggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaag
caggccuuugcucgaauauauuagcauggaauaauagaauaggacguuau
gguucuauuuuguugguuucuaggaccaucguaaugauuaauagggacgg
ucggggguaucaguauucaguugucagaggugaaauucuuggauuuacug
aagacuaacuacugcgaaagcauuuaccaaggacguuuucauuaaucaag
aacgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaacc
auaaacuaugccgacuagggaucgguuguuguucuuuuauugacgcaauc
ggcaccuuacgagaaaucaaagucuuuggguucuggggggaguauggucg
caaggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggag
ccugcggcuuaauuugacucaacacggggaaacucaccagguccagacac
aauaaggauugacagauugagagcucuuucuugauuuugugggugguggu
gcauggccguucuuaguugguggagugauuugucugcuuaauugcgauaa
cgaacgagaccuuaaccuacuaaauagugcugcuagcauuugcugguaua
gucacuucuuagagggacuaucgauuucaagucgauggaaguuugaggca
auaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuaca
cugacggagccagcgaguauaagccuuggccgagaggucugggaaaucuu
gugaaacuccgucgugcuggggauagagcauuguaauuguugcucuucaa
cgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauugaauggcuuagug
aggccuccggauugguuuaggaaauucuggaaccgagaagcuggucaaac
uuggucauuuagaggaaguaaaagucguaacaagguuuccguaggugaac
cugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<...............<<.....<..<
<.......>>..>......>>........<<<<<..<<....>>..>>>>
><...<<<<<<.......{.((((.<<<....>>>..............>
>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>
..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<.
..>>>>..>>>..>....>.>.....<<<<<<<<<<<<.....>>.>>>>
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>
>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<..
.......<..>.............>>>>>>>>>>.....<<<<.......
.............>>>>....<<<<<.<<.......<<...<.......>
..<<<....>>>....>>......>>.>>..>>>.........<<<..<<
<<<<<<<.....)))).}..>>>>>>>>>>>>.....>>....<<<<<<.
<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>
>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>...>
>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.
.........<<<.<<.<<<..<<<<<<<<..<<........>>.>>>>>>
>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<.
...>>>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<
<.<<<<<<......<<........>>..........<<<<<.<....<<<
<<........<<.<<<........>>>.>>......>>>>>...<<.<<<
..<<.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...>
>.>>>....<<<<<.<<..<<<<..<<<<.<<<<<<<....>>>>>>>..
..>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>..
...>>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>...
..<<<<<<<......<<......<<<.<<<<....>>>>.>>>....>>.
......>>>>>>>...........<<<<<<..........>>>>>>....
......>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<..<...<<<<<<<.<.<...>.>.>>>>>>>...>..>>>>..>>
>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>
>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c3a New crystal system to promote screening for new eukaryotic inhibitors
Resolution3.0 Å
Binding residue
(original residue number in PDB)		H3 V6 W7 F8 S9 H10 R12 F14 K16 G17 R19 C24 G29 L30 I31 R32 K33 Y34 R40 Q41 C42 R44 E45 K54 Y55 R56
Binding residue
(residue number reindexed from 1)		H1 V4 W5 F6 S7 H8 R10 F12 K14 G15 R17 C22 G27 L28 I29 R30 K31 Y32 R38 Q39 C40 R42 E43 K52 Y53 R54
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030445 yeast-form cell wall
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c3a, PDBe:8c3a, PDBj:8c3a
PDBsum8c3a
PubMed
UniProtA0A1D8PTR4|RS29A_CANAL Small ribosomal subunit protein uS14 (Gene Name=CAALFM_CR08480CA)

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