Structure of PDB 6zqg Chain DO Binding Site BS01

Receptor Information
>6zqg Chain DO (length=127) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAA
MLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGL
RIGRIEDVTPVPSDSTRKKGGRRGRRL
Ligand information
>6zqg Chain D3 (length=1387) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuauguugcaguuaaaaagcucguaguugaacuuugggcccgguuggcc
ggucggauuuccaacggggccuuuccuucuggcuaaccuugaguccuugu
ggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaa
gcaggcguauugcucgaauauauuagcauggaauaauagaauaggacguu
ugguucuauuuuguugguuucuaggaccaucguaaugauuaauagggacg
gucgggggcaucaguauucaauugucagaggugaaauucuuggauuuauu
gaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaa
gaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaac
cauaaacuaugccgacuagggaucgggugguguuuuuuuaaugacccacu
cggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaugguc
gcaaggcuaaagacggaagggcaccaccaggaguggagccugcggcuuac
acgcgcgcuacacugacggagccagcgagucuaaccuuggccgagagguc
uugguaaucuugugaaacuccgucgugcuggggauagagcauuguaauua
uugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguu
gauuacgucccugcccuuuguacacaccgcccgucgcuaguaccggaacu
aauuccguaggugaaccugcggaaggaucauuaaaga
<..<<<<<.......>>>>>.><..<<<<<<...<.<..........<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<..................<.....<<
.<<<.....>>>.>>......>.........<<<<<..<<....>>..>>
>>><.<.<<<<<<......((((((..<<<....>>>.............
.>>>>>>.>...>...<<<<..<<<.....>>>.>>>>....>>>...>>
>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<
.....>>>..>>>.......>.>.....<<<<<.................
...>>.>>>......<<..<...........>..>>.........<<<<<
<.......<<<....>>>..................>>>>>>..>>>>>>
.>.......<<<[[.....<.<<...<<<.<<....<<<<<<.<<<<<..
..........>>>>>.>>>>>>....<<<<<<.........<<<......
.>>>.........>>>>>>...<<<<<.<<.......<<...<.......
>..<<<.....>>>....>>......>>.>>..>>>.........<<<..
..<<<<<.......))))))..>>>>>...>>>.....>>....<<<<<<
.<<...<<<<..<<..<<<<<<.<...<<<..(...>>>......>.>>>
>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>...
>>.>....<<<<<<<...<...<<<<..)......>>>>...>>>>>>>>
..........<<<.<<.<<<..<<<<<<<<.<<<........>>>>>>>>
>>>..>>>...<<..]]>>...>>.....>>>.>>>..............
...........<<<<<<<<<<<<..<<.<<<<<...<<<.<<<<......
.>>>>.>>>.....<<<<<<<......<<.....<<..<<<<....>>>>
..>>....>>.......>>>>>>>...........<<<<<<.........
.>>>>>>...........>>>>>....<<<<<<<.........>>>>>>>
......>>...>>>>>>>............>>>>>..<<<<.<<>>.>>>
>.<<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqg 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		N24 D25 F27 H29 G35 K36 E37 T38 R41 T43 G45 D51 R52 E54 V121 P122 S123 D124 R127 G131 R132 R135 L137
Binding residue
(residue number reindexed from 1)		N14 D15 F17 H19 G25 K26 E27 T28 R31 T33 G35 D41 R42 E44 V111 P112 S113 D114 R117 G121 R122 R125 L127
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zqg, PDBe:6zqg, PDBj:6zqg
PDBsum6zqg
PubMed32943521
UniProtP06367|RS14A_YEAST Small ribosomal subunit protein uS11A (Gene Name=RPS14A)

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