Structure of PDB 4bts Chain DO Binding Site BS01

Receptor Information
>4bts Chain DO (length=152) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRMQMKGKGKGISGSALPFKRRSPKWLHMTPSTVVDLSVKLAKKGLTPSQ
IGVILRDQHGIPQVRFLTGQKILRILKKNGCAPQLPEDLYFLIKKALSIR
KHLEKNRKDKDSKYRLILVESRIHRLSRYYKLNQKLPPKWKYNAQTASAL
VQ
Ligand information
>4bts Chain DA (length=1717) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugauccugccaguuacauaugcuugucuuaaauauuaaccca
ugcaugugccaguucaguauugaacagcgaaacugcgaauggcucauuaa
aacaguuauaguuuauuugauaauuaaagauuacauggauaaccgagcua
auuguugggcuaauacaugcuuaaaauuccguguccugcgaccggaacgu
auuuauuagauauuagaccaaucgcagcaaugugauugagaugaaucaaa
guaacugaucggaucgagguuuaccucgauaaaucaucuaaguuucugcc
cuaucagcucucgaugguaguguauuggacuaccauggcagucacgggua
acggagaauuaggguucgauuccggagaaggagccugagaaacggcuacu
acaacuacgguucggcagcagggaagaaaauuggccaauccuaauucagg
gagccagugacaagaaauagcaagcugggaaacuuacguuucuacggcau
ugaaaugagaacaguguaaaucucuuagcgaggaacaauuggagggcaag
ucauggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugcaguuaaaaagcucguaguugaacuucuguucagguucauuuc
gauucgucgugugaaacuggacauacguuugcguaaacauuuuacuguga
aaaaauuagaguguuccaggcagguuuuagcccgaauacauuagcaugga
auaauggaauaggacuaaguccauuuuauugguucuuggauuugguaaug
auuaauagggacaguugggggcauuaguauuuaauagucagaggugaaau
ucuuggauuuauuaaggacuaacuaaugcgaaagcauuugccaaagaugu
uuucauuaaucaagaacgaaaguuaggggaucaaagacgaucagauaccg
ucguagucuuaacuauaaacuauaccgacucgggaucggcuggaauaaau
guccagucggcaccguaugagaaaucaaagucuuuggguucugggggaag
uaugguacgcaagucugaaacuuaaaggaauugacggaacagcacaccag
aaguggaaccugcggcuuaauuugacucaacacggggaaacucacgagcg
caagacagagaagggauugacagauugagagcucuuucuugauucuuugg
gugguggugcauggccguucuuaguugguggagugauuugucugguuaau
uccguuaacgaacgagaccuuaaccugcuaacuagucugcuuguaaauaa
cagguuguacuucuuagagggacuauugugcaauaagccaauggaaguuu
aaggcaauaacaggucugugaugccccuagacgugcucggccgcacgcgc
guuacaaugacuggcgcaaaaaguauuuccuguccugggaagguacgggu
aaucuuauuaauaccagucguguuagggauaguucuuuggaauuguggau
cuugaacgaggaauuucuaguaagugcaagucaucagcuugcguugauua
ugucccugccguuuguacacaccgcccgucgcuuguaguaacgaaugguc
uggugaaccuucuggacugcgacagcaauguugcggaaaaauaaguaaac
ccuaccauuuggaacaacaagaagucguaacaagguaucuguaggugaac
cugcagauggaucauua
...<<<<<.{.[[[[>>>>><.<.<<<<<<...<<<<.........<<<.
<<<..<<....<<...<<........>>...>>.>>......<<..<...
..<<<..<<..<<....<<<<..............<<.....<<.<<<..
...>>>.>>......>>.........<<<<<.<<<....>>>>>>>>.<.
..<<<<<........((((((..<<<....>>>......<......>..>
>>>>.....>...<<<<<<....>>>>>>...>>>>...>>>>..>>>.<
<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>..
.<<<<<<<<....>>>>...>>>>>>>.<<.<<<..........>>>.>>
..<<<....>>>.....>>>>>>.........<<<....<<<.....>>>
..>>>......>>>>.....<<<<<<<.<<<<<....>>>>>..>>>>.>
>>..........<<.........>>.............<<<<<((.....
...<<<.....<<..))>>.......>>>..>>>>>..>>>>>>.>.>..
.......<<<[[.....<.<<...<<<.<<....<<<<<<<.<<<<<..<
<<<..>>>>.>>>>>.>>>>>>>...<<<<<..>>>>>...<<<<<<<<.
......<<...<.......>..<<<....>>>....>>......>>>>>.
.>>>.........<<<<<<<<<<.....))))))..>>>>>>>>>>....
.>>....<<<<<<.<<...<<<<..<<..<<<<<<<<...<<<......>
>>......>>>>>>>>..>>.......<<....>>...>>>>...>>>>>
.>>>...>>>...>>.>...<<<<<<<<...<...<<<<.........>>
>>...>>>>>>>>>.........<<<.<<.<<<..<<<<<<<<<......
.>>>>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<...
...<<.<<....>>>>....>>>..]]]].}<<<<<.<<<.<<<.<<.<<
<<<<..<<<.<<<<<.......<<........>>..........<<<<<<
.....<<<<<<.......<<.<<<........>>>.>>.....>>>>>>.
..<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<.....
.>>>...>>.>>>....<<<<<.<<..<<<<..<<<..<<<<<<.....>
>>>>>...>>>..>>>>.>>....<<<<.<<.....>>>>>>.......>
>>>>....>>>.>>>...>.>>>>>>>......>>>>>>....>.>>>>.
>>>.....<<<<<<.......<<.....<<<<<<<<....>>>.>>>>>.
...>>........>>>>>>...........<<.<<<..........>>>.
>>..........>>>>>>....<<<<<<<<.......>>>>>>>>.....
.>>...>>>.>>>>>>.>>....<..<<.<.<<<<<.<<..<<<<<<<<.
.<<<..<<.<..<...<<<<<<<<....>>>>>>>>...>..>.>>..>>
>..>>>>>>>>..>>.>>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bts The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Resolution3.703 Å
Binding residue
(original residue number in PDB)
G2 R3 M4 Q5 M6 K7 G8 K9 K11 I13 S14 G15 S16 A17 L18 P19 R22 P49 S50 G53 R57 P63 R66 K72 L74 R75 E88 D89 F92 L93 K96 H103 K109 D110 K111 K114 Y115 R116 I118 L119 S122 R123 R126 R129 Y130
Binding residue
(residue number reindexed from 1)
G1 R2 M3 Q4 M5 K6 G7 K8 K10 I12 S13 G14 S15 A16 L17 P18 R21 P48 S49 G52 R56 P62 R65 K71 L73 R74 E87 D88 F91 L92 K95 H102 K108 D109 K110 K113 Y114 R115 I117 L118 S121 R122 R125 R128 Y129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4bts, PDBe:4bts, PDBj:4bts
PDBsum4bts
PubMed23851459
UniProtE6PBT1

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