Structure of PDB 8oeq Chain DN Binding Site BS01

Receptor Information
>8oeq Chain DN (length=97) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKKRASNGRNKKGRGHVKPVRCLNCARCVPKDKAIKRVTIRNMVEAAAVR
DLSEASVYAEYALPKLYNKLHYCVSCAIHARIVRVRSRTDRKIRTPP
Ligand information
>8oeq Chain CM (length=1726) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaauaac
uuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuucugc
ccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacgggu
aacggggaauaaggguucgauuccggagagggagccugagaaacggcuac
cacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacggg
gagguagugacaauaaauaacgauacaggguuguaauuggaaugaguaca
auguaaauaccuuaacgaggaacaauuggagggcaagucuggugccagca
gccgcgguaauuccagcuccaaaagcguauauuaaaguuguugcaguuaa
aaagcucguaguugaaccuugggcuuggcuggccgguccuggacccagcc
gagccuuuccuucuggguagccauuuauggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggccuuugcucgaauauauuagcaug
gaauaauagaauaggacguuaugguucuauuuuguugguuucuaggacca
ucguaaugauuaauagggacggucggggguaucaguauucaguugucaga
ggugaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuacc
aaggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauc
agauaccgucguagucuuaaccauaaacuaugccgacuagggaucgguug
uuguucuuuuauugacgcaaucggcaccuuacgagaaaucaaagucuuug
gguucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
gaaacucaccagguccagacacaauaaggauugacagauugagagcucuu
ucuugauuuugugggugguggugcauggccguucuuaguugguggaguga
uuugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauagu
gcugcuagcauuugcugguauagucacuucuuagagggacuaucgauuuc
aagucgauggaaguuugaggcaauaacaggucugugaugcccuuagacgu
ucugggccgcacgcgcgcuacacugacggagccagcgaguagccuuggcc
gagaggucugggaaaucuugugaaacuccgucgugcuggggauagagcau
uguaauuguugcucuucaacgaggaauuccuaguaagcgcaagucaucag
cuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuacua
ccgauugaauggcuuagugaggccuccggauugguuuagggaaccgagaa
gcuggucaaacuuggucauuuagaggaaguaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<.........((((.<<<....>>>..............>>>>>>.
....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.
<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>.
..<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>
>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>>>>
..>>>..>....>.>.....<<<<...<...>...>>>>......<<..<
...........>..>>.........<<<<<((......<<<<.....<<.
.))>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<[[..
...<.<<...<<<.<<....<<<<<<<<<<<<............>>>>>>
>>>>>>......<<......................>>.....<<<<<.<
<.......<<...<.......>..<<<....>>>....>>......>>.>
>..>>>.........<<<..<<<<<<<<<.....))))....>>>>>>>>
>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<
<......>>>......>.>>>>>>..>>.......<<....>>...>>>>
...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<.
....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<
<..<<........>>.>>>>>>>>..>>>...<<..]]>>...>>.....
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).}<<<<<.
<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>..
........<<<<<.<....<<<<<........<<.<<<........>>>.
>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.<<<<<....
>>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<
<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....<<<<<<...
..>>>>>>.......>>>>>.....>>.>>>.....>>>>>>>.....>.
>>>>>...>>.>>>>.>>>.....<<<<<<<......<<...<<<.<<<<
....>>>>.>>>....>>.......>>>>>>>...........<<<<<<.
.........>>>>>>..........>>>>>>....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<..<...<<<<<.......>>>>>...
>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<
<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)
P2 K3 K4 R5 A6 S7 N8 G9 R10 N11 K12 K13 G14 R15 G16 H17 K19 R28 K32 K34 K37 R38 V39 K70 V75 S76 I79 H80 R82 V84 R85 V86 R87 S88 R89 R92 R95 P98
Binding residue
(residue number reindexed from 1)
P1 K2 K3 R4 A5 S6 N7 G8 R9 N10 K11 K12 G13 R14 G15 H16 K18 R27 K31 K33 K36 R37 V38 K69 V74 S75 I78 H79 R81 V83 R84 V85 R86 S87 R88 R91 R94 P97
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