Structure of PDB 8cq7 Chain DN Binding Site BS01

Receptor Information
>8cq7 Chain DN (length=98) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKKRASNGRNKKGRGHVKPVRCLNCARCVPKDKAIKRVTIRNMVEAAAVR
DLSEASVYAEYALPKLYNKLHYCVSCAIHARIVRVRSRTDRKIRTPPQ
Ligand information
>8cq7 Chain CM (length=1765) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguaccuuacuacuuggauaaccgu
gguaauucuagagcuaauacaugcuuaaaaucccgacuguuuggaaggga
uguauuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucau
aauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaau
uucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuca
acggguaacggggaauaaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccga
cacggggagguagugacaauaaauaacgauacagggcccuuuugggucuu
guaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaaaagcguauau
uaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcugg
ccgguccauaugcguacuggacccagccgagccuuuccuucuggguagcc
auuuauggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaag
caggccuuugcucgaauauauuagcauggaauaauagaauaggacguuau
gguucuauuuuguugguuucuaggaccaucguaaugauuaauagggacgg
ucggggguaucaguauucaguugucagaggugaaauucuuggauuuacug
aagacuaacuacugcgaaagcauuuaccaaggacguuuucauuaaucaag
aacgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaacc
auaaacuaugccgacuagggaucgguuguuguucuuuuauugacgcaauc
ggcaccuuacgagaaaucaaagucuuuggguucuggggggaguauggucg
caaggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggag
ccugcggcuuaauuugacucaacacggggaaacucaccagguccagacac
aauaaggauugacagauugagagcucuuucuugauuuugugggugguggu
gcauggccguucuuaguugguggagugauuugucugcuuaauugcgauaa
cgaacgagaccuuaaccuacuaaauagugcugcuagcauuugcugguaua
gucacuucuuagagggacuaucgauuucaagucgauggaaguuugaggca
auaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuaca
cugacggagccagcgaguauaagccuuggccgagaggucugggaaaucuu
gugaaacuccgucgugcuggggauagagcauuguaauuguugcucuucaa
cgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauugaauggcuuagug
aggccuccggauugguuuaggaaauucuggaaccgagaagcuggucaaac
uuggucauuuagaggaaguaaaagucguaacaagguuuccguaggugaac
cugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<...............<<.....<..<
<.......>>..>......>>........<<<<<..<<....>>..>>>>
><...<<<<<<.........((((.<<<....>>>..............>
>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>
..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<.
..>>>>..>>>..>....>.>.....<<<<<<<<<<<<.....>>.>>>>
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>
>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<..
.......<..>.............>>>>>>>>>>.....<<<<.......
.............>>>>....<<<<<.<<.......<<...<.......>
..<<<....>>>....>>......>>.>>..>>>.........<<<..<<
<<<<<<<.....))))....>>>>>>>>>>>>.....>>....<<<<<<.
<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>
>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>...>
>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.
.........<<<.<<.<<<..<<<<<<<<..<<........>>.>>>>>>
>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<.
...>>>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<
<.<<<<<<......<<........>>..........<<<<<.<....<<<
<<........<<.<<<........>>>.>>......>>>>>...<<.<<<
..<<.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...>
>.>>>....<<<<<.<<..<<<<..<<<<.<<<<<<<....>>>>>>>..
..>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>..
...>>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>...
..<<<<<<<......<<......<<<.<<<<....>>>>.>>>....>>.
......>>>>>>>...........<<<<<<..........>>>>>>....
......>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<..<...<<<<<<<.<.<...>.>.>>>>>>>...>..>>>>..>>
>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>
>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.2 Å
Binding residue
(original residue number in PDB)
P2 K3 K4 R5 A6 S7 N8 G9 R10 N11 K12 K13 G14 R15 G16 H17 K19 R28 K32 K34 K37 R38 K70 V75 S76 I79 H80 R82 R85 V86 R87 S88 R89 R92 R95 P98
Binding residue
(residue number reindexed from 1)
P1 K2 K3 R4 A5 S6 N7 G8 R9 N10 K11 K12 G13 R14 G15 H16 K18 R27 K31 K33 K36 R37 K69 V74 S75 I78 H79 R81 R84 V85 R86 S87 R88 R91 R94 P97
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