Structure of PDB 8oeq Chain DJ Binding Site BS01

Receptor Information
>8oeq Chain DJ (length=129) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRTSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLTVMQKHGYIGEFE
YIDDHRSGKIVVQLNGRLNKCGVIQPRFNVKINDIERWTDNLLPARQFGY
VILTTSAGIMDHEEARRKHVSGKILGFVY
Ligand information
>8oeq Chain CM (length=1726) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaauaac
uuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuucugc
ccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacgggu
aacggggaauaaggguucgauuccggagagggagccugagaaacggcuac
cacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacggg
gagguagugacaauaaauaacgauacaggguuguaauuggaaugaguaca
auguaaauaccuuaacgaggaacaauuggagggcaagucuggugccagca
gccgcgguaauuccagcuccaaaagcguauauuaaaguuguugcaguuaa
aaagcucguaguugaaccuugggcuuggcuggccgguccuggacccagcc
gagccuuuccuucuggguagccauuuauggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggccuuugcucgaauauauuagcaug
gaauaauagaauaggacguuaugguucuauuuuguugguuucuaggacca
ucguaaugauuaauagggacggucggggguaucaguauucaguugucaga
ggugaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuacc
aaggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauc
agauaccgucguagucuuaaccauaaacuaugccgacuagggaucgguug
uuguucuuuuauugacgcaaucggcaccuuacgagaaaucaaagucuuug
gguucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
gaaacucaccagguccagacacaauaaggauugacagauugagagcucuu
ucuugauuuugugggugguggugcauggccguucuuaguugguggaguga
uuugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauagu
gcugcuagcauuugcugguauagucacuucuuagagggacuaucgauuuc
aagucgauggaaguuugaggcaauaacaggucugugaugcccuuagacgu
ucugggccgcacgcgcgcuacacugacggagccagcgaguagccuuggcc
gagaggucugggaaaucuugugaaacuccgucgugcuggggauagagcau
uguaauuguugcucuucaacgaggaauuccuaguaagcgcaagucaucag
cuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuacua
ccgauugaauggcuuagugaggccuccggauugguuuagggaaccgagaa
gcuggucaaacuuggucauuuagaggaaguaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<.........((((.<<<....>>>..............>>>>>>.
....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.
<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>.
..<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>
>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>>>>
..>>>..>....>.>.....<<<<...<...>...>>>>......<<..<
...........>..>>.........<<<<<((......<<<<.....<<.
.))>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<[[..
...<.<<...<<<.<<....<<<<<<<<<<<<............>>>>>>
>>>>>>......<<......................>>.....<<<<<.<
<.......<<...<.......>..<<<....>>>....>>......>>.>
>..>>>.........<<<..<<<<<<<<<.....))))....>>>>>>>>
>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<
<......>>>......>.>>>>>>..>>.......<<....>>...>>>>
...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<.
....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<
<..<<........>>.>>>>>>>>..>>>...<<..]]>>...>>.....
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).}<<<<<.
<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>..
........<<<<<.<....<<<<<........<<.<<<........>>>.
>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.<<<<<....
>>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<
<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....<<<<<<...
..>>>>>>.......>>>>>.....>>.>>>.....>>>>>>>.....>.
>>>>>...>>.>>>>.>>>.....<<<<<<<......<<...<<<.<<<<
....>>>>.>>>....>>.......>>>>>>>...........<<<<<<.
.........>>>>>>..........>>>>>>....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<..<...<<<<<.......>>>>>...
>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<
<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)
T2 R3 T4 V6 A8 D9 N12 N16 R28 S31 K32 H56 R57 K71 V74 I75 Q76 R78 F79 N80 K82 I83 R88 W89 T105 T106 S107 R118 K119 H120 S122 K124 Y130
Binding residue
(residue number reindexed from 1)
T1 R2 T3 V5 A7 D8 N11 N15 R27 S30 K31 H55 R56 K70 V73 I74 Q75 R77 F78 N79 K81 I82 R87 W88 T104 T105 S106 R117 K118 H119 S121 K123 Y129
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