Structure of PDB 6hiw Chain DJ Binding Site BS01

Receptor Information
>6hiw Chain DJ (length=315) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGYTPVNPDTSPMVAYSQYHWHYNLPQGMERPHSVNRTFAAPFQSNHSLV
NKYRGVWIEFDMHPAFSVALEPQLRKLPRGRTLPKTPAEEVIADYTALAP
LVDDEKTRDLWLAKVFQHCAFQRCGGAMELWERYCHQRFTAEGATAKPPL
SLVKSVLFYCNKTDNSGWRALFDRCLKDGWNYTPLFDTAQWSFMLKSIGR
MGDEDGVRAVLEEMLDVQADLDRVEARSVVIALNAVTNADVYEFVKKYLF
NFGERKVKFLRTTYSDLRGHGAGKLRIPLKENDNMYYHVCWHSSIRSPRQ
FSPRQLYFDYTPSTL
Ligand information
>6hiw Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
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uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
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....................<<<.......<<<<..............<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
..................................................
.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.<<<<<............................................
..................................................
.....................>>>>>..................>>....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution3.37 Å
Binding residue
(original residue number in PDB)		V10 G11 Y12 F52 N55 H56 S57 L58 K61 R63 D231 R232 E234 A235 R264 K265 F268 R270 T271 H279 K283
Binding residue
(residue number reindexed from 1)		V1 G2 Y3 F43 N46 H47 S48 L49 K52 R54 D222 R223 E225 A226 R255 K256 F259 R261 T262 H270 K274
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum6hiw
PubMed30213880
UniProtQ584U8

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