Structure of PDB 6hiv Chain DF Binding Site BS01

Receptor Information
>6hiv Chain DF (length=590) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVSGVFSKGRGIGHEATTSILRYIPRARVPWQPSRFGRENLTAADMARLW
SRGRYRDGPGNYNSGYCTERTHVLEENTVSIIPRRELEKYMPDITIGPKA
LVTPVSLMNARNGHRVTHDLLHSYDPHIGRLGKPAVVDHDNITVEDPNRV
GLNAATLDCRGRIYRWLRRGPFFQVDNYFRRSVKLNRDGTLPTDFVHEAP
LMRKIIRLAHRGHLKAACEEYRRVTTVPPVEVYRALTACCVPGAKLADAV
SIFEDGDSKLFYVSRDGEVLHNLMRCAIAARHRARIMWVYNVMRGRFYEN
VVVRAEVDLIWRYRIAMIALEYLLDHECAEEAAAIYSYLVEEELLRCDVH
VRVGLHMREAIAAGKPITLNNDVMNATSLVRDATAVAPEVARELQRRHAQ
TLQNNAVEAVGAGSAPWSILGPLTAIGPTAEDTMVWLQQHYGDVDVMSIM
RWARFRKGKDLMAKDRPQYLARAAAWIELLSKRNREMEEVPLTYMRKSKP
LVLDTNSNVRVAWQTPLMRSGGPPRLLAREEGYVFHHSNSSRFVEETYRH
PGESLQSRYLALQPLHTEVSAKEDFQRLYYQAQKHHKQQE
Ligand information
>6hiv Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
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....................<<<.......<<<<..............<.
..>..........................................<<...
.<<...<<<.......>>>..>>.......>>........<<....>>..
..................................................
.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.<<<<<............................................
..................................................
.....................>>>>>..................>>....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)
G10 R11 G12 I13 L22 I25 R27 R29 Q33 S35 R36 F37 N41 R49 L50 R53 G54 Y56 R57 N62 H128 R131 G133 K134 P135 A156 D159 R161 G162 R166 D177 R181 R182 K185 R188 S259 K260 R297 F298 Y299
Binding residue
(residue number reindexed from 1)
G9 R10 G11 I12 L21 I24 R26 R28 Q32 S34 R35 F36 N40 R48 L49 R52 G53 Y55 R56 N61 H127 R130 G132 K133 P134 A155 D158 R160 G161 R165 D176 R180 R181 K184 R187 S258 K259 R296 F297 Y298
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ38ET1

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